{"id":841,"date":"2025-12-25T04:12:16","date_gmt":"2025-12-25T04:12:16","guid":{"rendered":"https:\/\/vitalitynychealth.com\/?p=841"},"modified":"2026-04-09T22:21:16","modified_gmt":"2026-04-09T22:21:16","slug":"high-cholesterol-ignore-it-medicate-it-or-understand-it","status":"publish","type":"post","link":"https:\/\/vitalitynychealth.com\/ru\/2025\/12\/25\/high-cholesterol-ignore-it-medicate-it-or-understand-it\/","title":{"rendered":"High Cholesterol: Ignore It, Medicate It\u2026 or Understand It?"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"841\" class=\"elementor elementor-841\" data-elementor-post-type=\"post\">\n\t\t\t\t<div class=\"elementor-element elementor-element-57ed8b1 e-con-full e-flex e-con e-parent\" data-id=\"57ed8b1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-f5e9472 e-con-full e-flex e-con e-child\" data-id=\"f5e9472\" data-element_type=\"container\" 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elementor-widget-mobile__width-initial elementor-widget elementor-widget-heading\" data-id=\"dbba438\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">High Cholesterol: Ignore It, Medicate It\u2026 or Understand It?<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5abdc49 e-con-full e-flex e-con e-child\" data-id=\"5abdc49\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2c06539 elementor-widget elementor-widget-image\" data-id=\"2c06539\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"768\" height=\"571\" src=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-24.jpg\" class=\"attachment-full size-full wp-image-846\" alt=\"\" srcset=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-24.jpg 768w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-24-300x223.jpg 300w\" sizes=\"(max-width: 768px) 100vw, 768px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ac0f42d e-flex e-con-boxed e-con e-parent\" data-id=\"ac0f42d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-168bd5f elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"168bd5f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Modern guidelines\u2014based on decades of global research and endorsed by respected medical bodies like the <b>American College of Cardiology (ACC)<\/b>, <b>American Heart Association (AHA)<\/b>, and <b>National Institutes of Health (NIH):<\/b><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>Total Cholesterol<\/b>: below <b>200 mg\/dL<\/b>, with <b>150 mg\/dL<\/b> considered even better Readings of <b>240 mg\/dL or higher<\/b> are categorized as high.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>LDL Cholesterol<\/b> (\u201cbad\u201d cholesterol): The goal is <b>below 100 mg\/dL<\/b> for most people, and <b>below 70 mg\/dL<\/b> for those considered high-risk.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>Triglycerides<\/b>: Normal levels are <b>under 150 mg\/dL<\/b>. Anything above <b>200 mg\/dL<\/b> is considered high (very high if over <b>500 mg\/dL<\/b>)<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Individuals with the lowest serum cholesterol or LDL-C levels carry the least risk. In other words, \u2018the lower, the better\u2019 for cholesterol levels holds.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-46c67bd e-flex e-con-boxed e-con e-parent\" data-id=\"46c67bd\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-f5b73dc e-con-full e-flex e-con e-child\" data-id=\"f5b73dc\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d4e0303 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"d4e0303\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Who Should Take Statins?<span style=\"color:#0C802D\">(And Why It Depends)<\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e70daa9 elementor-icon-list--layout-traditional elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"e70daa9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t\t\t\t<ul class=\"elementor-icon-list-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">Statins consistently recommend\u00a0 as the <b>first-line treatment<\/b>, especially when paired with lifestyle changes.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>Secondary Prevention\u00a0\u00a0\u00a0 <\/b>If someone has already been diagnosed with cardiovascular disease\u2014whether it\u2019s a <b>heart attack, angina, stroke<\/b>, or <b>peripheral arterial disease<\/b>\u2014they should be on a <b>high-intensity statin<\/b>. Why? Because the data is clear: statins dramatically lower the risk of repeat events and death in these patients.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>Primary Prevention\u00a0 <\/b>For those <b>without diagnosed heart disease<\/b>, statin use is based on risk factors:<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>LDL \u2265 190 mg\/dL<\/b>: Treatment is strongly recommended This level is often genetically driven and carries a very high lifetime risk.<\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>Adults with diabetes (age 40\u201375)<\/b><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item\">\n\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-caret-right\" viewBox=\"0 0 192 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M0 384.662V127.338c0-17.818 21.543-26.741 34.142-14.142l128.662 128.662c7.81 7.81 7.81 20.474 0 28.284L34.142 398.804C21.543 411.404 0 402.48 0 384.662z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><b>Adults (age 40\u201375) with LDL 70\u2013189 mg\/dL<\/b> and a calculated <b>10-year ASCVD risk \u22657.5<\/b><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0aee754 e-con-full e-flex e-con e-child\" data-id=\"0aee754\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-d224bc3 elementor-widget elementor-widget-image\" data-id=\"d224bc3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1460\" src=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-25.jpg\" class=\"attachment-full size-full wp-image-860\" alt=\"\" srcset=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-25.jpg 2560w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-25-300x171.jpg 300w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-25-1024x584.jpg 1024w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-25-768x438.jpg 768w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-25-1536x876.jpg 1536w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-25-2048x1168.jpg 2048w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-08c4e6e e-flex e-con-boxed e-con e-parent\" data-id=\"08c4e6e\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2e822e6 elementor-widget elementor-widget-heading\" data-id=\"2e822e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Evidence Supporting <span style=\"color:#0C802D\">Statin Guidelines<\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-06164d5 elementor-widget elementor-widget-text-editor\" data-id=\"06164d5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Grounded in decades of high-quality evidence from well-designed randomized controlled trials (RCTs) and large meta-analyses the Cholesterol Treatment Trialists\u2019 (CTT) Collaboration, which combined data from 26 large trials, found that for every 1 mmol\/L (~39 mg\/dL) reduction in LDL, there was an average 22% reduction in major vascular events, and LDL reduction2 mmol\/L (77 mg\/dL) reduction corresponds to an approximate 45% reduction in such events.<\/p>\n<p>This finding has been confirmed by multiple meta-analyses showing that long-term statin therapy reduces the risk of death from both vascular and non-vascular causes.<\/p>\n<p>Statins are also effective in individuals who have not yet been diagnosed with any vascular disease. This is referred to as primary prevention. Studies such as WOSCOPS (in men with elevated LDL levels) and JUPITER (in individuals with high inflammatory markers, like CRP, but normal LDL levels) found that statins significantly lowered the risk of first-time events\u2074.<\/p>\n<p>Summary Taken together, this extensive research supports a clear consensus: Maintaining lower LDL cholesterol levels is strongly associated with better long-term health outcomes. When prescribed appropriately, the benefits of statin therapy outweigh the risks in the vast majority of individuals. This makes statins a cornerstone of preventive care option, considered thoughtfully, based on evidence and individual context.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-94938f8 e-flex e-con-boxed e-con e-parent\" data-id=\"94938f8\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-40863ef e-con-full e-flex e-con e-child\" data-id=\"40863ef\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ae2b39e elementor-widget elementor-widget-heading\" data-id=\"ae2b39e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A Different Perspective: The Case for <span style=\"color:#0C802D\">Cholesterol Skepticism<\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-0fd9ff3 elementor-widget elementor-widget-text-editor\" data-id=\"0fd9ff3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>While the mainstream medical consensus strongly supports lowering LDL cholesterol and using statins when indicated, not everyone agrees. An alternative viewpoint\u2014supported by some practitioners in functional and integrative medicine, select cardiologists and researchers, and increasingly by health influencers\u2014challenges the dominant \u201clower is better\u201d model. This perspective has sparked a growing interest in what some now call \u201ccholesterol skepticism.\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4979851 elementor-widget elementor-widget-heading\" data-id=\"4979851\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Historical Context: How Did We Go from \u201cNormal\u201d 300 to \u201cHigh\u201d 200?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2648958 elementor-widget elementor-widget-text-editor\" data-id=\"2648958\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>During the 1970s, many physicians reportedly viewed total cholesterol below 300 mg\/dL as unremarkable. Critics argue that over time, cholesterol thresholds were progressively lowered, which may have expanded the number of people eligible for medication. Some suggest that this trend was influenced, in part, by pharmaceutical interests, since lower targets mean more prescriptions.<\/p><p>Formal definitions also evolved. For instance, the NIH\u2019s NCEP guidelines in 1987 redefined \u201cdesirable\u201d total cholesterol as less than 200 mg\/dL\u2014a shift from previous norms\u00b2. For alternative health advocates, this suggests that cholesterol targets are a moving goalpost, not necessarily rooted in universal biology.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-e043510 e-con-full e-flex e-con e-child\" data-id=\"e043510\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-464c251 elementor-widget elementor-widget-image\" data-id=\"464c251\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1707\" src=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-26.jpg\" class=\"attachment-full size-full wp-image-898\" alt=\"\" srcset=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-26.jpg 2560w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-26-300x200.jpg 300w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-26-1024x683.jpg 1024w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-26-768x512.jpg 768w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-26-1536x1024.jpg 1536w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-26-2048x1366.jpg 2048w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-a8d53e3 e-flex e-con-boxed e-con e-parent\" data-id=\"a8d53e3\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f2a364b elementor-widget elementor-widget-heading\" data-id=\"f2a364b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">A Different Interpretation of the <span style=\"color:#0C802D\">Data <\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a2fff3b elementor-widget elementor-widget-text-editor\" data-id=\"a2fff3b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Cholesterol skeptics often argue that moderately elevated cholesterol levels\u2014particularly in older adults\u2014may not be harmful and might even be physiologically appropriate. They point to observational studies suggesting that in some age groups, higher cholesterol levels correlate with better longevity, not worse outcomes.<\/p><p>One frequently cited example comes from a BMJ review of cohort studies in people over age 60. That review found no consistent association between high LDL and cardiovascular death in many older populations\u2014and in some cases, an inverse relationship with all-cause mortality\u00b3. In simpler terms, some groups of older adults with higher LDL seemed to live longer than those with lower levels.<br \/>This idea has gained traction on social media and in books promoting natural health. The result is a popular claim that looks something like this: Claim (Alternative View): \u201cOlder people with high LDL do not die prematurely \u2013 they actually live the longest, outliving both those with untreated low LDL and those on statin treatment.\u201d<\/p><p>From this perspective, cholesterol\u2019s role as a \u201cvillain\u201d in cardiovascular disease may be overstated, particularly in aging populations. Some proponents argue that cholesterol may play protective roles\u2014such as supporting hormone synthesis or immune function\u2014especially in later life or during illness.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c6e1201 e-flex e-con-boxed e-con e-parent\" data-id=\"c6e1201\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-913b2ce e-con-full e-flex e-con e-child\" data-id=\"913b2ce\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b395f1f elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"b395f1f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">The <span style=\"color:#0C802D\">\u201cCholesterol Myth\u201d?<\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c4a4d94 elementor-widget elementor-widget-text-editor\" data-id=\"c4a4d94\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>A central idea promoted by this movement is what they call the \u201ccholesterol myth\u201d\u2014the belief that cholesterol itself is not the main cause of vascular disease, and that inflammation, insulin resistance, or other metabolic factors may be more significant contributors.<\/p><p>\u00a0<\/p><p>This doesn\u2019t mean they reject all treatments or preventive care. Instead, they often emphasize nutrition, lifestyle, metabolic health, and inflammation control over medication. They also advocate for personalized risk assessment, rather than treating cholesterol as a universal danger.<\/p><p>\u00a0<\/p><p>While this viewpoint remains controversial in the academic and clinical world, it resonates with many patients who are hesitant to take medication for a symptomless condition and who feel overwhelmed by the evolving nature of guidelines and public messaging.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-1c63631 e-con-full e-flex e-con e-child\" data-id=\"1c63631\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a985ded elementor-widget elementor-widget-image\" data-id=\"a985ded\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1707\" src=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-27.jpg\" class=\"attachment-full size-full wp-image-909\" alt=\"\" srcset=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-27.jpg 2560w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-27-300x200.jpg 300w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-27-1024x683.jpg 1024w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-27-768x512.jpg 768w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-27-1536x1024.jpg 1536w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-27-2048x1366.jpg 2048w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-0748d8c e-flex e-con-boxed e-con e-parent\" data-id=\"0748d8c\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-eb29c02 elementor-widget elementor-widget-heading\" data-id=\"eb29c02\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><span style=\"color:#0C802D\">The Benefit<\/span>  in Low-Risk People Is Small <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-17ca3bc elementor-widget elementor-widget-text-editor\" data-id=\"17ca3bc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>One of the primary arguments is that statins offer only modest absolute benefits for people without prior cardiovascular events. Critics often cite statistics such as: \u201cYou have to treat 100 people for 5 years to prevent just one heart attack.\u201d<\/p><p>These statements are meant to illustrate the low absolute risk reduction in primary prevention. A widely referenced analysis by Kristensen et al. (2015) reviewed multiple clinical trials and found that, for many users, statins did not significantly extend lifespan.<br \/>In fact, that review calculated the median gain in survival was only a few days or weeks for most people\u2014approximately 3 days in primary prevention and 4 days in secondary prevention\u00b9.<\/p><p>This leads some patients and practitioners to ask:<br \/>\u201cIf I\u2019m otherwise healthy, is it really worth taking a medication every day for the rest of my life for a benefit I\u2019ll likely never feel?\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-215af49 e-flex e-con-boxed e-con e-parent\" data-id=\"215af49\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-8337626 elementor-widget elementor-widget-heading\" data-id=\"8337626\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Questions about blood <span style=\"color:#0C802D\">markers<\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e762701 elementor-widget elementor-widget-heading\" data-id=\"e762701\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Does LDL Even Matter?<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8ba229a elementor-widget elementor-widget-text-editor\" data-id=\"8ba229a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>A more controversial criticism goes further: challenging the idea that LDL is the cause of cardiovascular disease.<br \/>A 2018 review led by Uffe Ravnskov and colleagues questioned the cholesterol hypothesis entirely, suggesting that many studies show no clear link between high LDL and heart disease, and that other factors might be more important\u00b2. They highlight cases where people with low LDL still suffer from cardiovascular events, and where those with high LDL remain healthy into old age. This has led to the popular notion that:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7f8a0eb elementor-widget elementor-widget-heading\" data-id=\"7f8a0eb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u201cCholesterol is just an innocent bystander.\u201d<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-153c190 elementor-widget elementor-widget-text-editor\" data-id=\"153c190\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Proponents of this view suggest the real drivers of disease may be inflammation, oxidative stress, or insulin resistance, not cholesterol itself. They also argue that cholesterol plays essential roles in the body, such as supporting hormone production, brain function, cell membrane integrity<\/p><p>This leads to concerns that aggressively lowering LDL might have unintended negative consequences, especially in aging adults.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b691f67 elementor-widget elementor-widget-heading\" data-id=\"b691f67\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">\u201cMy grandfather had a cholesterol level of 280 and lived to 90.\u201d<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b807cd2 elementor-widget elementor-widget-heading\" data-id=\"b807cd2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Alternative Risk Markers<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b2b435c elementor-widget elementor-widget-text-editor\" data-id=\"b2b435c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Because of this broader interpretation, many practitioners outside of conventional cardiology shift focus away from LDL alone and instead emphasize other markers, such as:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-517fb57 elementor-widget elementor-widget-text-editor\" data-id=\"517fb57\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul>\n<li>C-reactive protein (CRP) \u2013 a marker of systemic inflammation<\/li>\n<li>Triglyceride-to-HDL ratio \u2013 sometimes seen as a better predictor of metabolic risk<\/li>\n<li>Coronary artery calcium score \u2013 used to assess actual plaque burden in arteries<\/li>\n<li>These providers often recommend a more individualized and holistic approach, prioritizing overall metabolic health and inflammation control rather than aiming for specific cholesterol numbers.<\/li>\n<\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-9d26938 e-flex e-con-boxed e-con e-parent\" data-id=\"9d26938\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t<div class=\"elementor-element elementor-element-693c57f e-con-full e-flex e-con e-child\" data-id=\"693c57f\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-74f90b9 elementor-widget elementor-widget-heading\" data-id=\"74f90b9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Emphasis on Side Effects and <span style=\"color:#0C802D\">Potential Risks of Statins<\/span> <\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6671193 elementor-widget elementor-widget-text-editor\" data-id=\"6671193\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Emphasis on Side Effects and Potential Risks of Statins:<br \/>One of the most frequently voiced concerns from statin skeptics is the potential for side effects.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7fb9090 elementor-widget elementor-widget-heading\" data-id=\"7fb9090\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Muscle Symptoms and Fatigue:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-968e5d0 elementor-widget elementor-widget-text-editor\" data-id=\"968e5d0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Dr. Mark Hyman, a functional medicine practitioner, frequently cites that up to 20% of statin users report notable muscle discomfort or weakness.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3615637 elementor-widget elementor-widget-heading\" data-id=\"3615637\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Blood Sugar and Metabolic Effects:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4861cbb elementor-widget elementor-widget-text-editor\" data-id=\"4861cbb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>statins can slightly increase the risk of developing type 2 diabetes, estimate a ~9\u201312% relative increase in diabetes incidence over time.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e3c6286 elementor-widget elementor-widget-heading\" data-id=\"e3c6286\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Cognitive and Neurological Concerns:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b8bc8f6 elementor-widget elementor-widget-text-editor\" data-id=\"b8bc8f6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>memory issues or cognitive changes. While the FDA has acknowledged that rare, reversible cognitive problems may occur, critics believe these cases may be underreported or not well understood. One possible mechanism that is sometimes discussed is the reduction of Coenzyme Q10 (CoQ10) levels.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-65d0191 elementor-widget elementor-widget-heading\" data-id=\"65d0191\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Liver Function and Hormonal Effects<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-23d6651 elementor-widget elementor-widget-text-editor\" data-id=\"23d6651\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Severe liver damage from statins is very rare, and routine liver monitoring is no longer required for all patients<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-007c21d e-con-full e-flex e-con e-child\" data-id=\"007c21d\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t<div class=\"elementor-element elementor-element-ad0a4d7 elementor-widget elementor-widget-image\" data-id=\"ad0a4d7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1544\" src=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-28.jpg\" class=\"attachment-full size-full wp-image-907\" alt=\"\" srcset=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-28.jpg 2560w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-28-300x181.jpg 300w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-28-1024x618.jpg 1024w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-28-768x463.jpg 768w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-28-1536x926.jpg 1536w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-28-2048x1235.jpg 2048w\" sizes=\"(max-width: 2560px) 100vw, 2560px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7e66bf1 e-flex e-con-boxed e-con e-parent\" data-id=\"7e66bf1\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-a88b8e9 elementor-widget elementor-widget-heading\" data-id=\"a88b8e9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><span style=\"color:#0C802D\">Critique<\/span>   of Pharmaceutical Influence and Medical Guidelines<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b019325 elementor-widget elementor-widget-text-editor\" data-id=\"b019325\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Critics point out that many experts involved in writing cholesterol guidelines or conducting statin trials have received consulting fees or research funding from drug manufacturers. For example, a group of physicians in the UK published a letter in 2014 noting that 8 of 12 experts on a major NICE guideline panel had financial ties to statin-producing companies.<\/p><p>Expanding Definitions = Expanding Markets. Another criticism is that pharmaceutical companies benefit when cholesterol thresholds are lowered, as more people become eligible for treatment.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f09792a elementor-widget elementor-widget-heading\" data-id=\"f09792a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Concerns About Selective Publication and \u201cHidden\u201d Data:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f873fc elementor-widget elementor-widget-text-editor\" data-id=\"5f873fc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Skeptics also worry that statin trial data is largely controlled by pharmaceutical sponsors, and that: Negative or neutral results may go unpublished; Raw data on side effects may not be released for independent analysis; Published results may selectively highlight benefits over risks Validating Patient Concerns: Another critique is that mainstream medicine may not always listen to or validate patient-reported side effects. When patients express concerns like muscle pain or fatigue, they\u2019re sometimes told, \u201cit\u2019s just aging\u201d or \u201cit\u2019s in your head.\u201d<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-be507bd e-flex e-con-boxed e-con e-parent\" data-id=\"be507bd\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-f27717f elementor-widget elementor-widget-image\" data-id=\"f27717f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img loading=\"lazy\" decoding=\"async\" width=\"903\" height=\"473\" src=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-29.jpg\" class=\"attachment-full size-full wp-image-906\" alt=\"\" srcset=\"https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-29.jpg 903w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-29-300x157.jpg 300w, https:\/\/vitalitynychealth.com\/wp-content\/uploads\/2025\/12\/the-web-guys1-29-768x402.jpg 768w\" sizes=\"(max-width: 903px) 100vw, 903px\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4559a4a elementor-widget elementor-widget-heading\" data-id=\"4559a4a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">This chart compares the population analyzed during the most commonly used reference publications  for mainstream medicine ( green) vs the alternative point of view (red)<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-afdc045 elementor-widget-mobile__width-initial elementor-widget elementor-widget-text-editor\" data-id=\"afdc045\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\tCDC\u00a0\u2013\u00a0<i>\u201cAbout\u00a0Cholesterol\u201d<\/i>,\u00a0optimal\u00a0levels\u00a0and\u00a0definitions\n\nNCBI\/Endotext\u00a0\u2013\u00a0Grundy\u00a0et\u00a0al.,\u00a0<i>\u201cGuidelines\u00a0for\u00a0High\u00a0Blood\u00a0Cholesterol\u201d<\/i>,\u00a0on\u00a0benefits\u00a0of\u00a0lowering\u00a0LDL\n(22%\u00a0risk\u00a0reduction\u00a0per\u00a039\u00a0mg\/dL)\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0\u00a0and\u00a0ACC\/AHA\u00a0guideline\u00a0highlights\n\nMercola\u00a0J.\u00a0\u2013\u00a0<i>\u201cCholesterol\u00a0Does\u00a0Not\u00a0Cause\u00a0Heart\u00a0Disease\u201d\u00a0<\/i>(Alt\u00a0perspective\u00a0summary)\n\nMark\u00a0Hyman\u00a0MD\u00a0\u2013\u00a0<i>\u201cShould\u00a0I\u00a0Stop\u00a0My\u00a0Statins?\u201d\u00a0<\/i>(functional\u00a0medicine\u00a0view\u00a0on\u00a0side\u00a0effects)\nPharmaTimes\u00a0\u2013\u00a0<i>\u201cNICE\u00a0defends\u00a0statin\u00a0guidance\u00a0as\u00a0docs\u00a0attack\u00a0pharma\u00a0bias\u201d\u00a0<\/i>(COI\u00a0and\u00a0skeptic\u00a0letter)\n\nTCTMD\u00a0\u2013\u00a0Collins\u00a0et\u00a0al.\u00a0Lancet\u00a0statin\u00a0review\u00a0(benefit-risk\u00a0numbers)\n\nCleveland\u00a0Clinic\u00a0\u2013\u00a0<i>\u201cCholesterol\u00a0Levels\u00a0&amp;\u00a0Numbers\u201d\u00a0<\/i>(mainstream\u00a0targets,\u00a0no\u00a0LDL\u00a0lower\u00a0limit)\n\nACC\u00a0CardioSmart\u00a0\u2013\u00a0<i>\u201cNatural\u00a0Alternatives\u00a0to\u00a0Statins\u201d\u00a0<\/i>(overview\u00a0of\u00a0supplements)\n\nAbout\u00a0Cholesterol\u00a0|\u00a0Cholesterol\u00a0|\u00a0CDC\n<a href=\"https:\/\/www.cdc.gov\/cholesterol\/about\/index.html\">https:\/\/www.cdc.gov\/cholesterol\/about\/index.html\u00a0<\/a>\n\nCholesterol:\u00a0Understanding\u00a0Levels\u00a0&amp;\u00a0Numbers\n<a href=\"https:\/\/my.clevelandclinic.org\/health\/articles\/11920-cholesterol-numbers-what-do-they-mean\">https:\/\/my.clevelandclinic.org\/health\/articles\/11920-cholesterol-numbers-what-do-they-mean\u00a0<\/a>\n\nCholesterol\u00a0Does\u00a0Not\u00a0Cause\u00a0Heart\u00a0Disease\u00a0<a href=\"https:\/\/articles.mercola.com\/sites\/articles\/archive\/2022\/08\/09\/cholesterol-myth-what-really-causes-heart-disease.aspx\">https:\/\/articles.mercola.com\/sites\/articles\/archive\/2022\/08\/09\/cholesterol-myth-what-really-causes-heart-disease.aspx\u00a0<\/a>\n\nGuidelines\u00a0for\u00a0the\u00a0Management\u00a0of\u00a0High\u00a0Blood\u00a0Cholesterol\u00a0&#8211;\u00a0Endotext\u00a0&#8211;\u00a0NCBI\u00a0Bookshelf\u00a0<a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK305897\/\">https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK305897\/<\/a>\n\n2018\u00a0AHA\/ACC\/AACVPR\/AAPA\/ABC\/ACPM\/ADA\/AGS\/APhA\/ASPC\u00a0&#8230;\u00a0<a href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/cir.0000000000000625\u00a0\">https:\/\/www.ahajournals.org\/doi\/10.1161\/cir.0000000000000625\u00a0<\/a>\n\nacc.org\u00a0<a href=\"https:\/\/www.acc.org\/~\/media\/Non-Clinical\/Files-PDFs-Excel-MS-Word-etc\/Guidelines\/2018\/Guidelines-Made-Simple-Tool-2018-Cholesterol.pdf\">https:\/\/www.acc.org\/~\/media\/Non-Clinical\/Files-PDFs-Excel-MS-Word-etc\/Guidelines\/2018\/Guidelines-Made-Simple-Tool-2018-<\/a><a href=\"https:\/\/www.acc.org\/~\/media\/Non-Clinical\/Files-PDFs-Excel-MS-Word-etc\/Guidelines\/2018\/Guidelines-Made-Simple-Tool-2018-\">\u00a0<\/a>\n<a href=\"https:\/\/www.acc.org\/~\/media\/Non-Clinical\/Files-PDFs-Excel-MS-Word-etc\/Guidelines\/2018\/Guidelines-Made-Simple-Tool-2018-Cholesterol.pdf\">Cholesterol.pdf<\/a>\n\nReview\u00a0Touts\u00a0Benefits\u00a0of\u00a0Statins,\u00a0Seeks\u00a0to\u00a0Dispel\u00a0Safety\u00a0Concerns\u00a0|\u00a0tctmd.com\u00a0<a href=\"https:\/\/www.tctmd.com\/news\/review-touts-benefits-statins-seeks-dispel-safety-concerns\u00a0\">https:\/\/www.tctmd.com\/news\/review-touts-benefits-statins-seeks-dispel-safety-concerns\u00a0<\/a>\n\nImpact\u00a0of\u00a0renal\u00a0function\u00a0on\u00a0the\u00a0effects\u00a0of\u00a0LDL\u00a0cholesterol\u00a0&#8230;\u00a0&#8211;\u00a0PubMed\n<a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/27477773\/\">https:\/\/pubmed.ncbi.nlm.nih.gov\/27477773\/\u00a0If you agree to try a statin, schedule a follow-up in 6\u20138 weeks. Discuss side effects openly.\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-8eb9580 e-flex e-con-boxed e-con e-parent\" data-id=\"8eb9580\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-439334e elementor-widget elementor-widget-heading\" data-id=\"439334e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Comparing the <span style=\"color:#0C802D\">Two Perspectives:<\/span>    Strengths, Weaknesses, and Clinical Implications<\/h2>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-c9ffdb0 e-con-full e-flex e-con e-child\" data-id=\"c9ffdb0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-edad64a e-con-full e-flex e-con e-child\" data-id=\"edad64a\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2f0dfe0 elementor-widget elementor-widget-heading\" data-id=\"2f0dfe0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Scientific Rigor and Evidence-Based: Mainstream Perspective:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d4eed18 elementor-widget elementor-widget-text-editor\" data-id=\"d4eed18\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>The conventional stance is built on a robust body of peer-reviewed clinical research and are updated regularly by expert panels who review the totality of available data.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-d5aba38 e-con-full e-flex e-con e-child\" data-id=\"d5aba38\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-7f2829f elementor-widget elementor-widget-heading\" data-id=\"7f2829f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Scientific Rigor and Evidence-Based:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-defe298 elementor-widget elementor-widget-text-editor\" data-id=\"defe298\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><b>\u00a0<\/b>Alternative Perspective<br \/>View draws on observational studies and re-analyses of data. Some of its proponents are MDs or PhDs who publish thoughtful critiques\u2014though often in lower-tier or specialty journals. This group emphasizes clinical relevance over statistical significance: a central argument is that the absolute benefit of statins is small for many individuals, and that the focus should be on personalized risk, not population averages.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ae2abf0 e-con-full e-flex e-con e-child\" data-id=\"ae2abf0\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-c0d1c5e e-con-full e-flex e-con e-child\" data-id=\"c0d1c5e\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-5812266 elementor-widget elementor-widget-heading\" data-id=\"5812266\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Patient-Centered Care and Autonomy:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a8c7cb9 elementor-widget elementor-widget-text-editor\" data-id=\"a8c7cb9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Mainstream Perspective. Modern guidelines now emphasize shared decision-making, particularly for primary prevention. Clinicians are encouraged to discuss the benefits, risks, and patient values before recommending statins\u2074.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2702907 e-con-full e-flex e-con e-child\" data-id=\"2702907\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-adb4782 elementor-widget elementor-widget-heading\" data-id=\"adb4782\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Patient-Centered Care and Autonomy:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9ff7e81 elementor-widget elementor-widget-text-editor\" data-id=\"9ff7e81\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Alternative and functional medicine providers tend to be highly patient-focused, often spending more time discussing lifestyle, stress, sleep, and emotional health. This approach empowers patients who want to avoid medication, take control of their health through diet and behavior changes, and feel respected in the process.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2992932 e-con-full e-flex e-con e-child\" data-id=\"2992932\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-ab0f64f e-con-full e-flex e-con e-child\" data-id=\"ab0f64f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-b38dfe8 elementor-widget elementor-widget-heading\" data-id=\"b38dfe8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Mainstream Clinicians:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ab2451c elementor-widget elementor-widget-text-editor\" data-id=\"ab2451c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Tend to use quantitative language:<\/p><p><i>\u201cYou have a 10-year risk of 20%. A statin reduces that by 25%.\u201d<\/i><\/p><p>Often refer to population-level data, which may not feel personally relevant to patients.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-5e275ee e-con-full e-flex e-con e-child\" data-id=\"5e275ee\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e683518 elementor-widget elementor-widget-heading\" data-id=\"e683518\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Alternative Clinicians:<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ad9a89c elementor-widget elementor-widget-text-editor\" data-id=\"ad9a89c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Use more metaphors and intuitive explanations:<br \/><i>\u201cLet\u2019s cool the inflammation in your arteries by fixing your diet.\u201d<\/i><\/p><p>Focus on how the patient feels, not just what the lab shows.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-7b66027 e-flex e-con-boxed e-con e-parent\" data-id=\"7b66027\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-688af49 elementor-widget elementor-widget-heading\" data-id=\"688af49\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"> <span style=\"color:#0C802D\">Risk<\/span> \u2013Benefit Analysis of Statin Use<\/h2>\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-db902b9 e-con-full e-flex e-con e-child\" data-id=\"db902b9\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t<div class=\"elementor-element elementor-element-f47c9ef e-con-full e-flex e-con e-child\" data-id=\"f47c9ef\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-97e889e elementor-widget elementor-widget-text-editor\" data-id=\"97e889e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p><b>Mainstream Medical Interpretation<\/b><\/p><p>For patients who meet guideline criteria, particularly those at <b>moderate to high risk<\/b>, the consensus from major organizations is clear:<br \/><b>Statins provide significant benefit, and the risks are small and manageable.<\/b><\/p><p>To illustrate, here\u2019s what the research shows: In a group of <b>10,000 patients treated with statins over 5 years<\/b>, studies estimate that statins may prevent:<br \/>: \u2013 <b>500 to 1,000 major cardiovascular events<\/b> (such as heart attacks, strokes, and procedures)<br \/>\u2013 While causing approximately:<br \/>\u2013 <b>50 new cases of diabetes<\/b><br \/>\u2013 <b>5 cases of serious muscle injury<\/b>\u00b9<\/p><p>When framed this way, the scale tips strongly in favor of benefit, especially in those with established cardiovascular disease or a high baseline risk.\u00a0<\/p><p>It\u2019s also worth noting that:\u00a0 <b>Most side effects are reversible<\/b>. If a patient develops muscle pain or elevated liver enzymes, the symptoms <b>usually resolve after stopping or switching the medication<\/b>.<\/p><p>In contrast, <b>cardiovascular damage<\/b>\u2014such as a stroke or heart attack\u2014can result in <b>permanent disability or death<\/b>, making the consequences of untreated high risk potentially far more serious than the common side effects of therapy\u00b2.<\/p><p><b>Long-Term Safety-Risk of Side Effects: Context and Management\u00a0<\/b><\/p><p>Concerns have also been raised about whether statins may have long-term negative effects outside of the cardiovascular system (e.g., cancer risk, memory loss, or non-cardiac mortality). To date:<\/p><p><b>Large meta-analyses have shown no increase in deaths from non-cardiac causes<\/b>, such as cancer\u00b3.<\/p><p>In fact, in <b>high-risk groups<\/b>, statins are associated with a <b>reduction in overall (all-cause) mortality<\/b>\u2014not just fewer cardiac events.<\/p><p>This means that patients who are likely to benefit from statins may not only avoid a heart attack, but may <b>live longer overall<\/b>, without evidence of increased risk in other health domains.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-99f3470 e-con-full e-flex e-con e-child\" data-id=\"99f3470\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t<div class=\"elementor-element elementor-element-0a32cfc elementor-widget elementor-widget-text-editor\" data-id=\"0a32cfc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>While the mainstream medical community emphasizes population-level benefits of statins, <b>the alternative view focuses more on individual-level tradeoffs<\/b>, particularly in people with <b>low to moderate risk<\/b>. This perspective doesn\u2019t deny that statins reduce LDL and cardiovascular events\u2014it questions whether the <b>magnitude of that benefit justifies lifelong medication<\/b>, especially for those who feel well and have no prior history of vascular disease.<\/p><p><b>Focus on Absolute Risk Reduction\u00a0 <\/b><\/p><p>A key argument is the difference between <b>relative and absolute risk<\/b>. For example: If someone has a <b>10-year cardiovascular risk of 10%<\/b>, and statins reduce that risk to <b>~7%<\/b>,<br \/>the <b>absolute risk reduction is only 3%<\/b>. That means 97 out of 100 people would <b>not have had an event either way<\/b>.<\/p><p>This leads to the commonly heard challenge: <i>\u201cWhy expose 100 people to side effects to help 3 avoid an event?\u201d<\/i><\/p><p>This framing emphasizes the <b>Number Needed to Treat (NNT)<\/b>\u2014how many people must take the drug for one person to benefit\u2014and contrasts it with the <b>Number Needed to Harm (NNH)<\/b>, which may be <b>closer than commonly acknowledged<\/b> if side effects are underreported or underestimated.<\/p><p><b>Quality of Life and Day-to-Day Impact<\/b><\/p><p>The alternative view also centers on <b>quality of life<\/b>. If even <b>5\u201310%<\/b> of statin users experience <b>muscle pain, fatigue, or cognitive effects<\/b>, that\u2019s potentially more people affected negatively than those helped in low-risk groups.<\/p><p>As one skeptic summarized:<br \/><i>\u201cStatins slightly tilt the long-term odds\u2014but at what cost to how I feel today?\u201d<\/i><\/p><p>This concern becomes even more pressing in people who are active, sensitive to medications, or managing multiple health priorities.<\/p><p><b>Long-Term Uncertainty<\/b><\/p><p>Another issue raised is the <b>lack of long-term data over several decades<\/b>. Most statin trials last 3\u20135 years. Skeptics ask:<\/p><p>What happens after <b>30 years of continuous statin use<\/b>?<\/p><p>Could there be <b>subtle cognitive or metabolic effects<\/b> that only emerge with extended exposure?<\/p><p>Are we fully aware of what prolonged inhibition of cholesterol synthesis does to <b>hormonal, neurological, or immune function<\/b>?<\/p><p>Mainstream experts counter that we now have <b>real-world experience with millions of patients on statins for 20+ years<\/b>, and <b>no major late-emerging risks have been observed<\/b>. In fact, these patients often <b>live longer<\/b>. Still, the <b>desire for caution<\/b> remains a core value in the alternative camp.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-42ee43f e-flex e-con-boxed e-con e-parent\" data-id=\"42ee43f\" data-element_type=\"container\" data-e-type=\"container\" data-settings=\"{&quot;background_background&quot;:&quot;classic&quot;}\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-236d687 elementor-widget elementor-widget-heading\" data-id=\"236d687\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\"><span style=\"color:#0C802D\">Integrative Synthesis:<\/span>   The Best of Both Worlds<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-022c063 elementor-widget elementor-widget-text-editor\" data-id=\"022c063\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>While mainstream and alternative perspectives diverge in strategy and interpretation, they ultimately share a common goal: preventing cardiovascular disease and optimizing patient health. A thoughtful synthesis that blends the scientific rigor of conventional guidelines with the individualized, lifestyle-focused ethos of functional medicine may offer the most balanced and patient-resonant care.<\/p><p>Statins are a powerful, evidence-based tool\u2014but they are not a panacea, nor the only tool. Lifestyle remains the cornerstone of cardiovascular prevention, and patients\u2019 beliefs, values, and preferences must be honored.<\/p><p>The effort to self-educate is essential. However, it is also crucial to understand the quality and scientific value of the information source.<br \/>Use online calculators or even coronary artery calcium (CAC) scans to see your actual risk, not a generic one. If someone\u2019s CAC is zero, they may reasonably delay statins. If it\u2019s high, the risk becomes more tangible\u2014and so does the need for medication.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b6f2465 elementor-widget elementor-widget-heading\" data-id=\"b6f2465\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Make Lifestyle the Common Ground<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-298e292 elementor-widget elementor-widget-text-editor\" data-id=\"298e292\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>Taking a statin is not a substitute for a healthy lifestyle\u2014it\u2019s an extra layer of protection.<br \/>Collaborate on diet and physical activity goals.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9b67313 elementor-widget elementor-widget-heading\" data-id=\"9b67313\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">Monitor Closely and Follow Up Early.<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b8c4a68 elementor-widget elementor-widget-text-editor\" data-id=\"b8c4a68\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p>If you agree to try a statin, schedule a follow-up in 6\u20138 weeks. Discuss side effects openly.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>HOME \/ Page Title High Cholesterol: Ignore It, Medicate It\u2026 or Understand It? Modern guidelines\u2014based on decades of global research and endorsed by respected medical bodies like the American College of Cardiology (ACC), American Heart Association (AHA), and National Institutes of Health (NIH): Total Cholesterol: below 200 mg\/dL, with 150 mg\/dL considered even better Readings [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":846,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[9],"tags":[],"class_list":["post-841","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.4 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>High Cholesterol: Ignore It, Medicate It\u2026 or Understand It? - Svetlana Pyatigorskaya NP in Family Health PC<\/title>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"ru_RU\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"High Cholesterol: Ignore It, Medicate It\u2026 or Understand It? - Svetlana Pyatigorskaya NP in Family Health PC\" \/>\n<meta property=\"og:description\" content=\"HOME \/ Page Title High Cholesterol: Ignore It, Medicate It\u2026 or Understand It? 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